Harrison Favored Over Nunes Again at UFC 334 in NYC
UFC 334 odds have Kayla Harrison favored at -190 over Amanda Nunes, who is +161 for their MSG title fight.

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Kayla Harrison opened as a -190 favorite over Amanda Nunes in their UFC 334 co-main event, with Nunes sitting at +161 on the latest odds board as the former two-division champion steps back into title contention at Madison Square Garden.
UFC 334 lands Nov. 14 at MSG, with Ciryl Gane defending the heavyweight title against unbeaten Josh Hokit in the main event. Gane opened at -243 to Hokit's +203. Harrison puts her women's bantamweight belt on the line against Nunes in the co-headliner, and the number tells its own story: the promotion's biggest star of the last decade is walking in as the betting underdog in a title fight for just the second time in her UFC career.
Why Nunes Is an Underdog Against Harrison
Nunes has only once before taken a completed UFC bout as the betting underdog, and it came against Cris Cyborg at UFC 232. Nunes last entered a completed UFC bout as an underdog against Cris Cyborg at UFC 232 in 2018. She won by knockout in 51 seconds. That result is part of why this line matters so much to bettors: Nunes has made a habit of outperforming the number when the market doubts her, and sportsbooks clearly remember it even while still favoring Harrison this time.
Harrison's case for favoritism is straightforward. She's undefeated in the Octagon and has run through the bantamweight division since arriving from PFL, and the -190 price reflects a champion in her prime facing a legend who hasn't fought in two years and is moving up to challenge at 135 pounds. For bettors, the gap between -190 and the kind of number a prime Nunes would have carried against most of the current roster is the real story. The market is pricing in ring rust and Harrison's physicality, not doubting Nunes's resume.
The Rest of the UFC 334 Main Card
The middleweight bout between Caio Borralho and Yousri Belgaroui carries the tightest line on the card. The middleweight matchup between Caio Borralho (-120) and Yousri Belgaroui (+103) has the closest betting line on the main card. That kind of number signals a genuinely competitive style matchup worth a second look for anyone betting the undercard.
Elsewhere, Uros Medic (-165) is favored against Kevin Holland (+140), a fight with finish potential given both men's willingness to stand and trade. The lopsided number on the card belongs to the flyweight bout between Bilal Hasan and Luis Gurule. Flyweight prospect Bilal Hasan is the main card's biggest favorite at -950 against Luis Gurule, a +650 underdog. A number that extreme leaves little betting value on the moneyline and pushes sharper action toward method-of-victory or round props if books offer them.
Betting Angle
The co-main event is the number worth watching as fight week approaches. A -190/+161 split is a real gap but not a blowout line, and it's tight enough that early movement in either direction will say a lot about how the market is reading Nunes's layoff versus Harrison's in-cage dominance. Given Nunes's track record of outperforming underdog odds in meaningful spots, bettors weighing value on the co-main would be wise to track whether that number holds or tightens before fight night. The heavyweight title fight, by contrast, already reflects a clear consensus, with Gane's -243 number pricing him as a comfortable favorite over the undefeated but significantly less experienced Hokit.
Frequently Asked Questions
What are the odds for Kayla Harrison vs. Amanda Nunes at UFC 334?
Kayla Harrison opened as a -190 favorite over Amanda Nunes, who is listed at +161, for their women's bantamweight title fight at UFC 334 on Nov. 14 at Madison Square Garden.
Has Amanda Nunes ever been an underdog in the UFC before?
Yes, Amanda Nunes previously entered a completed UFC bout as an underdog against Cris Cyborg at UFC 232 in 2018 and won by knockout in 51 seconds.
Who is the main event of UFC 334?
Ciryl Gane defends his UFC heavyweight title against unbeaten contender Josh Hokit in the UFC 334 main event at Madison Square Garden, with Gane favored at -243.


